The Brannigan Research Group was formed in Fall 2011 and is located in the Physics Department and Center for Computational and Integrative Biology at the Camden campus of Rutgers University. We use high performance computing approaches to investigate the biophysics of proteins, membranes, and small molecules, with a heavy emphasis on Molecular Dynamics Simulation with atomic resolution. One research theme concerns proteins involved in function and pharmacology of the central nervous system, with a particular focus on the mechanisms underlying the effects of disease-associated single nucleotide polymorphisms or the actions of modulators such as neurosteroids or anesthetics. An additional research theme involves the interactions of transmembrane proteins with lipids, including cholesterol. A list of current research projects can be found here.
The group includes members from a range of backgrounds, including biology, pharmacology, physical chemistry, and physics. Interested Masters and PhD students may apply to the graduate program in Computational and Integrative Biology at RU-C, while those interested in a post-doctoral position should email the PI directly with a CV and cover letter stating how their research background fits in with the group’s aims.